The SV40 t and T antigen coding region was ligated to the murine Pcp2 promoter region. The Pcp2 promoter restricted expression to Purkinje cells. The founder line carried 10 copies of the transgenic construct. (J:79857)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count