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An intronic floxed neo cassette was removed by crossing to a cre-expressing deleter strain, leaving behind a tyrosine to phenylalanine knock-in mutation at position 315 (Y315F). Expression of the mutant allele was confirmed by sequence analysis of RT-PCR products from thymus of mutant animals. (J:71099)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
