Log In|Sign Up
EN
A portion of exon 1 and all of exons 2 and 3 were replaced by a cassette containing both lacZ and neo. The insertion was designed to delete the 3' promoter (in intron 1) and leave lacZ under the control of the 5' promoter located upstream of exon 1. Beta-galactosidase expression was verfied by staining. The absence of endogenous transcript and protein was confirmed by Northern and Western blot analyses. (J:79500)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
