The gene was disrupted by insertion of a neomycin resistance cassette into exon 1 via homologous recombination. Northern blot analysis failed to detect gene expression in any of the tissues examined from homozygous mutant animals (brain, heart, kidney, liver, and lung). (J:49644)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count