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The floxed neo cassette was removed from Esrtm1Lja by in vivo cre mediated recombination. The glutamate to alanine and glycine to alanine missense mutations at codons 207 and 208 were left intact. Expression of mutant transcript and protein was verified by RT-PCR and Western blot analyses of liver tissue. (J:79228)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
