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A 920 bp fragment encompassing the Frat1 coding region was adjoined to the Pim1 promoter region and 2 immunoglobulin heavy chain enhancers (E-mu). The Frat1 coding region was followed by a Moloney murine leukemia virus (MoMuLV) long terminal repeat. Northern blot analysis detected expression of the the transgene in all tissues tested. This founder line harbored 2 to 3 copies of the transgenic construct. (J:59555)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
