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This allele is derived from Hoxb4tm2Nrm. Embryos from heterozygous Hoxb4tm2Nrm intercrosses were injected with a cre expression plasmid to remove the floxed neo cassette in the first coding exon. The deletion leaves behind a 78 bp insertion containing a loxP site in the first exon. The 78 bp insertion contains a stop codon in-frame with the Hoxb4 transcript. (J:71389)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
