A loxP site was inserted upstream of Tcra-C element C1, and a loxP flanked neo was inserted between elements C3 and C4 via homologous recombination. Transient transfection of targeted ES cells removed the neo cassette leaving the conditional Calpha allele with C1, C2 and C3 flanked by loxP sites. (J:79298)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion, Intergenic deletion
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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