The gene was disrupted by replacement of exons 4 and 5 with a PGK-neo cassette in the reverse orientation. Northern blot analysis of brain RNA using a full-length cDNA probe confirmed the null allele in homozygous mutant animals. (J:77273)
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The gene was disrupted by replacement of exons 4 and 5 with a PGK-neo cassette in the reverse orientation. Northern blot analysis of brain RNA using a full-length cDNA probe confirmed the null allele in homozygous mutant animals. (J:77273)