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The coding regions of exons 2 through 5 were replaced by a neo cassette inserted by homologous recombination. In all, sequence encoding 250 of the 256 amino acids was deleted. Transcript was undetected by Northern blot analysis of total spleen RNA obtained from 4 week old homozygous mutant mice. (J:35827)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
