The complete transcription unit of the mouse Plp gene, including 3.5 kb of 5' regulatory sequence was used to create this transgenic mouse. Lines 66 and 72 were generated (7 and 3 copies of the transgene respectively). Lines 66 and 72 were generated (7 and 3 copies of the transgene respectively). (J:17373)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA)F2
--
Insertion
--
1
--
21

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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