671 bp of coding sequence were replaced by the insertion of a neomycin selection cassette into exon 2. Transcript was undetected in liver, uterus, and kidney tissue by RT-PCR analysis and in situ hybridization of kidney tissue. Western blot analysis of Prkcl1 protein expression indicated that the targeting vector did not significantly disrupt the the Prkcl1 locus, which putatively overlaps the Ptger1 locus. (J:79387)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
DBA/1LacJ
Targeted
Insertion
--
1
--
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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