The entire coding region of human DMD plus 190 bp of the 3' untranslated region was used as the transgene. The rat Acta1 promoter, exon 1, intron 1, and part of exon 2, was used to drive transgene expression in skeletal muscle. Expression of the transgene was confirmed by Western blot analysis of skeletal muscle tissue. (J:22142)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(BALB/cJ x C57BL/6)F1
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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