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The transgene is composed of Dmd cDNA sequences from exon 1 and exons 63-79 which encode the C-terminus of the full-length protein. The transgene is fused to mouse the Ckmm promoter/enhancer, exon 1, intron 1, and part of exon 2, which drives espression in skeletal muscle. Specific expression of the transgene in skeletal and cardiac tissue of transgenic animals was confirmed by Western blot analysis. (J:21841)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
