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The complete Tpm2 cDNA sequence and 3' untranslated region was used for the transgene. The transgene is expressed in adult heart tissue under the control of the Myhca promoter, which includes the 5' untranslated region and exons 1-3. Phosphoimaging analysis revealed a 150-fold and 34-fold increase in gene and protein expression, respectively, in hearts of transgenic animals. (J:30336)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
