LoxP sites flanking exon 3 and an upstream neo cassette were introduced to the gene via homologous recombination. A loxP site and a neo cassette were inserted upstream of the flanked exon. (J:71845)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count