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A construct containing a nonsense mutation at cysteine codon 199 was inserted at the endogenous locus via homologous recombination. Termination of translation after glycine 198 putatively precludes autoproteolytic activity and the associated process in which a cholesterol, involved in cell surface tethering, is attached to glycine 198. (J:69771)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
