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A lacZ-neo cassette was inserted in-frame into exon 7, resulting in a fusion protein and deletion of exons 8-10. Normal transcripts were not observed in homozygous mutant animals as shown by Northern blot analysis. The fusion protein was detected by Western blot of embryonic fibroblast lysates derived from homozygous mutant embryos. (J:67273)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
