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A neomycin selection cassette was inserted proximally to exon 3 via homologous recombination. Northern blot analysis of ES cells showed normal length transcript present at approximately 5% of wild-type levels. Subsequent sequence analysis identified a slice site between the neo cassette and exon 3, allowing a low rate of normal splicing to occur. (J:78546, J:79389)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
