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Exon 1 was flanked by loxP sites inserted into the 5' untranslated region and intron 1. The presence of the loxP sites were shown to have no effect on expression, as the levels of mRNA in liver and of protein in plasma, liver, heart, kidney were found to be normal by Northern and Western blot analyses. (J:67961)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
