This transgene expresses cre recombinase under the control of the dopachrome tautomerase promoter, active in pigment cells. Two lines (3469 and 3510) were crossed to reporter animals and analyzed further. Data for 3469 is shown in the original reference, but this line died out due to disease and line 3510 was continued. Only some line 3510 animals expressed the transgene sufficiently to allow detection of recombinase activity, and it was further determined that the line is a germ-line deleter strain. (J:79094)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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