Sequence encoding exons 2 through 7 were flanked by single loxP sites inserted into introns 1 and 7 in inverse orientations. A neo cassette was also inserted immediately downstream of the intron 7 loxP site. Mice carrying this allele were bred with transgenic mice expressing cre recombinase to generate Stk11tm2.1Tpm. (J:70892)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count