Log In|Sign Up
EN
Exons 1 through 7 were replaced by homologous recombination of a cassette containing GFP and neo. Southern blot analysis confirmed that the targeting vector hybridized exclusively to Ren1 and not to Ren2. RT-PCR analyses of kidney tissue confirmed the absence of endogenous transcript in homozygous mutant mice. Expression of GFP was verified in both heterozygous and homozygous mutant mice. (J:72077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
