The entire coding region of the gene was deleted and replaced with a PGK-neo cassette via homologous recombination. Northern blot analysis of RNA from the duodenum, jejunum, and colon of homozygous mutant animals did not detect gene expression. In situ hybridization of E9.5 homozygous mutant embryos also failed to detect gene transcripts. (J:54198)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion, Intragenic deletion
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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