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A full-length Mdm2 coding sequence (including introns 7 and 8) fused to the bovine beta-lactoglobulin (BLG) promoter, active in mammary glands, was used as the transgene. RNase protection assay of total RNA from mid-lactation mammary glands confirmed expression of the transgene intransgenic animals and detected both spliced and unspliced forms. Overexpression of the transgene was estimated to be 10-30 times that of the endogenous gene. (J:72124)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
