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EN
Sequence encoding conserved amino acids 75 through 86 (YSDLNTQRQYR) of the immunoreceptor tyrosine-based activation motif (ITAM) was replaced with a vector containing a floxed neo cassette followed by sequence encoding a putatively non-functional 15 amino acid peptide (GLQEFIEDEKKKRNSI). Mice carrying this allele were bred with transgenic mice expressing cre via the ubiquitous CMV promoter to generate Tyrobptm1.1Viv. (J:64764)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
