A cassette containing lacZ and neo was inserted in frame into exon 1. While expression of beta-galactosidase was driven by the endogenous promoter, neither endogenous transcript nor protein was detected in homozygous mice by RT-PCR and Western blot analyses. (J:66970)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count