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A 220 bp fragment of the gene containing exon 1 was replaced with a floxed neomycin cassette via homologous recombination. Protein expression was absent in bone marrow-derived mast cells (BMMC) and natural killer cells (NK) from homozygous mutant animals as determined by immunoprecipitation immunoblot assay. (J:64504)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
