The gene was disrupted by insertion of a neomycin resistance cassette in the reverse orientation into exon 4 via homologous recombination. Western blot analysis of spleen lysates from homozygous mutant animals did not detect protein product. (J:64349)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count