Rarg^tm3.1Ipc

The floxed fragment containing exon 8 was excised from Rargtm3Ipc by the ubiquitous in vivo expression of cre recombinase. The deletion eliminated the majority of the DNA binding domain and introduced a frameshift mutation. A lack of protein expression was demonstrated in homozygous mutant mice via immunohistochemical analysis of skin sections. (J:75133)