Exon 8, which encodes most of the DNA binding domain, was left flanked by loxP sites after the in vitro cre-mediated excision of a selection cassette. Immunohistochemical analysis showed that protein expression was not affected by the presence of the loxP sites. (J:75135)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count