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An activated form of human NR1I2 cDNA fused a mouse liver-specific albumin promoter was used as the transgene. A sequence from the herpes simplex virus VP16 activation domain at the amino terminus of NR1I2 confers activated status to the human protein. Expression of the human transgene was verified by Northern blot analysis of liver tissue from transgenic animals. (J:63639)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
