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The gene was tagged by insertion of an IRES-lacZ-floxed neo cassette 3' to the stop codon. Transient expression of cre recombinase in correctly targeted ES cells removed the floxed neo cassette prior to blastocyst injection. Whole-mount histochemical analysis and in situ hybridization confirmed that the expression pattern of the tagged gene in the olfactory sensory neurons is similar to that of wild-type. (J:64893)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
