A loxP site was introduced into intron 3 and a floxed PGK-neo-tk cassette was introduced into intron 4 via homologous recombination. The PGK-neo-tk cassette was subsequently removed in correctly targeted cells by the transient expression of cre recombinase, leaving behind loxP sites flanking exon 4. (J:48085)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion
--
1
--
29

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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