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A single copy of a construct in which the entire coding region was replaced with a hygromycin cassette was incorporated at the endogenous locus via homologous recombination. Transcript was undetected by RT-PCR analysis of bone marrow cells obtained from homozygous mutant mice. The absence of protein surface expression was confirmed by FACS analysis. (J:67609)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
