Multiple copies of a transgenic construct containing the sequence of human PDE5A inserted in tandem at the Theg locus, deleting approximately 20 kb of the genomic locus. Northern blot analysis of testis mRNA showed homozygous transgenic animals lacked transcripts of the Theg gene. (J:62271)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C3H
--
Insertion, Intragenic deletion
Recessive
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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