The neo gene was inserted in the opposite orientation via homologous recombination at a splice junction between intron 8 and exon 9a, which also deletes 32 bp of endogenous DNA. Northern blot of E8.5 embryos using probes to exon 9a and exon 9d did not detect gene transcripts in homozygous mutants. (J:44952)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
Insertion, Intragenic deletion
--
1
7
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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