This transgene was produced using a vector that contained the 2.4kb full-length mouse Cyp 19 cDNA in addition to a coding region that included -45 to -1 of 5' and a complete (860bp) 3' untranslated region under the control of a mouse mammary tumor virus promoter (MMTV). Multiple lines were generated, ranging in copy number from 1 to 30, estimated by Southern blot. This allele is representative of the high copy number variants and carries an estimated 20 copies of the gene in mammary gland tissue. (J:34063)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x BALB/c)F1
--
Insertion
--
1
--
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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