The entire coding region of the endogenous locus was flanked by a loxP site inserted into the untranslated region of exon 1 and a floxed neo cassette insertered downstream of the stop codon. (J:75126)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count