This allele, possessing sequence encoding enhanced green fluorescent protein in place of a portion of exon 1 encdoding the first 72 amino acids, was generated by breeding mice carrying Hoxa2tm2Fmr with mice expressing cre recombinase in the germline. Expression of EGFP detected in heterozygous mutant embryos followed the expression pattern of the endogenous gene. The deleted region corresponded to the region targeted in Hoxa2tm1Ipc. (J:75129)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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