A portion of exon 1, encoding the first 72 amino acids, was replaced via the insertion of the enhanced green fluorescent protein (EGFP) and a floxed neo cassette. Expression of EGFP was undetected, putatively due to the presence of the neo cassette. The deleted region corresponded to that in the conventionally targeted Hoxa2tm1Ipc. (J:75129)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
2
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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