The entire coding region was left floxed after the breeding of mice possessing Hoxa2tm1Fmr with transgenic mice expressing Flp recombinase, which resulted in the excision of the frt flanked neo cassette from the 3' untranslated region. RT-PCR analysis of embryos homozygous for this allele showed expression levels to be reduced by 10% to 15% relative to the expression levels determined in wild-type embryos. (J:75130)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
Insertion
--
1
2
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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