The ubiquitous expression of cre recombinase resulted in the excision of the neo cassette from Trp63tm3Brd. Exons 5 through 7, encoding the DNA-binding domain, were left flanked by single loxP sites in introns 4 and 7. (J:75125)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count