This allele lacks exons 2 and 3, which encode a portion of the DNA-binding high mobility group domain and the entire transactivation domain. It can be derived from Sox9tm1Gsr by cre recombinase excision of the loxP-flanked region containing exons 2 and 3 or from Sox9tm2Gsr by simultaneous excision of exons 2 and 3 and of a loxP-flanked neo cassette (which has been deleted in Sox9tm1Gsr). (J:75124)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
10
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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