A construct, in which the coding region of exon 1 was flanked by a single loxP site in the 5' untranslated region and a floxed neo cassette in intron 1, was incorporated at the endogenous locus via homologous recombination. (J:75123)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count