Floxed sequence including exon 2 and a neomycin cassette was excised from Men1tm1Gfk by the expression of cre recombinase. Exon 2 contained the initiator methionine and 400 bp of coding sequence. Western blot analysis showed an absence of encoded protein in homozygous mutant embryos. (J:75116)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129T2/SvEms
Targeted
Intragenic deletion
--
1
23
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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