Human E2F1 cDNA was adjoined to the bovine keratin 5 promoter, active in the basal cell compartment of stratified squamous epithelia. Expression of the human transgene was detected in basal keratinocytes by Northern blot analysis. Western blot analysis showed that the level of transgenic protein was 80 fold greater than that of the endogenous protein. (J:46535)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL/J)F2
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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