Exon 1 of the gene was flanked by an upstream loxP site and a downstream floxed neo cassette. Northern blot and RT-PCR analysis showed reduced levels of transcript in mutant mice. (J:75110)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count