Log In|Sign Up
EN
This allele was generated by breeding mice carrying Tcf1tm1Ylee with transgenic mice expressing cre via the EIIa promoter. Cre mediated excision of the floxed fragment, containing the coding region of exon 1 and the neo transgene inserted into intron 1, resulted in the loss of sequence encoding 108 amino acids as well as a portion of intron 1. Transcript was undetected in homozygous mutant mice via RT-PCR analysis. (J:47008)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
