Exons 16 through 21 were flanked by loxP sites inserted by homologous recombination. The floxed region contains sequence encoding portions of the DNA-binding and SH2 domains common to alpha and beta isoforms. (J:53586, J:78088)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count